デカルト 私は私が存在していることを知っている 真理を確保するために宗教、「神の誠実」を援用
One who went beyond him in posing questions of skepticism was René Descartes (1596–1650). Without specific precedent in the ancient materials, he set out to answer the skeptical idea that there could be an all-powerful malin genie or evil demon that manipulates human perceptions and reasoning, fooling people about the world. His conclusion was that individuals know of their existence because they can think—the famous "I think therefore I am." Explaining why one's perceptions of thinking could not be a deception, Descartes asserts that God would not allow such deception. Religion is invoked to certify truth. Later skeptics would worry about a deceiving God.
Pierre-Daniel Huet(1630–1721) ：セクスタスを援用してデカルトを徹底的に批判(1723)
Bishop Pierre-Daniel Huet (1630–1721) and the Huguenot refugee Pierre Bayle (1647–1706) have been described as the "master skeptics." Huet invoked Sextus Empiricus in great detail against Descartes and many other dogmatic philosophers in his Traité philosophique de la foiblesse de l'esprit humaine (1723; Philosophical tract on the weakness of the human mind). Bayle's massive works attacked all previous philosophy and historical scholarship but upheld moral rigorism.